Proof of Concept

California Clinical Trials (CCT) maintains uniformity in conducting well-powered proof of concept studies in the target population (n=150-200), in areas such as ratings, procedures, regulatory documents, and scientific and medical leadership.

Our four clinical sites ensure Sponsors meet standards of consistency and reliability for POC. And a single point of contact guides your study through the regulatory and contracts processes.

We combine sensitive and reliable efficacy determinations with a unique charting method to systematically capture all observations, including adverse events. We can combine PK sampling, complex circadian based assessments, and frequent sponsor-investigator conference calls to ensure a true partnership in ongoing research. CCT's track record for Phase IB/IIA Proof of Concept Studies also includes the development of compounds for both psychiatric and neurological disorders.

CCT has experience with cutting edge compounds and therapeutic classes including:

  • Neuropeptide modulators targeting Substance P and opioid systems
  • CRF and Cortisol modulators
  • Novel transporter inhibitors for neurotransmitters
  • Triptans
  • Novel antipsychotic agents with widely varying pharmacological profiles
  • A wide array of therapies for Alzheimer's Disease (treatment and disease modification)
  • Immunological modifiers for CNS processes

 

Click here to contact us about your Proof of Concept study.

Related Links